Your Outsourcing Partner for
Protein Research and Production Services
Exon BioSystems is a protein contract research and production services
company specializing in recombinant protein expression, protein
purification, and protein characterization.
Additional areas of expertise include assay
development of G-protein coupled receptor, recombinant vaccine
development and recombinant antibody production.
At the post-genomic era, the enormous demand of
recombinant proteins for high throughput screen, function research
and the time-consuming and laborious production of functional
proteins made recombinant protein a bottleneck. By developing new
techniques in protein expression and purification, Exon BioSystems
provide solutions to break the bottle neck for you.
If you want to make a
recombinant protein without a right gene in hands, Exon BioSystems
provides services to generate the gene for you. With multiple
conventional molecular techniques, such as gene cloning from
cDNA libraries, gene synthesis from synthesized oligos, we
can generate any gene you want.
If your research needs some
modifications of a gene, such as truncation, deletion, insertion,
point mutation, domain swapping or gene fusion, Exon BioSystems
provides the expertise such as Site-directed Mutagenesis and
conventional molecular techniques to help you reach your goal.
Using multiple expression
systems, including bacterial, insect and mammalian expression
systems, ExonBio has the capability to produce “hard to express
proteins”, such as membrane proteins, at milligram level. Whether
you’re focused on lead discovery, assay development, vaccine
production, high throughput screening, or characterization of
interesting gene products, We can find a solution for you.
No matter recombinant
proteins were used in assay development, formulation, high
throughput screen or protein characterization, one critical aspect
is that expected functional activity must be associated with a
targeted protein and a formulation must be devoid of any
contaminants including endotoxin and virus etc. It is imperative,
therefore, that therapeutic proteins, recombinant vaccines and
diagnostic proteins be purified to highest level possible.
Combining our skills
developed over the past ten years in protein biochemistry, and
partnering with ProteinX lab, we delivers efficient and cost
effective solutions in protein purification.
To meet the needs of our
clients, Exon provides protein characterization of our expressed
protein to insure the quality of recombinant protein. Routinely SDS-PAGE
and western blot will be carried out to acess the purity of the expressed
protein. N-terminal sequencing and Mass-spectrum are
available if clients request such services. As part of the protein
characterization, Exon provides functional assay to recombinant