Influenza B NP Monoclonal Antibody, 50-3B4

FB-50-3B4FB-50-3B4

Price range: $250.00 through $450.00

Product Name Anti-Influenza B rabbit monoclonal antibody, 50-3B4
Catalog Number FB-50-3B4
Immunogen Influenza B Nucleoprotein
Host Rabbit
Preparation Recombinant monoclonal antibody expressed in HEK293F cells and purified by protein A affinity chromatography.
Applications Any application that detects Influenza B virus, pseudo virus, and Influenza B native nucleocapsid protein. Does not detect denatured nucleocapsid protein.
Reactivity Influenza B nucleocapsid protein
Isotype rabbit IgG, kappa
Conjugation Unconjugated
Clonality Monoclonal
Concentration 1mg/ml
Purification Protein A affinity chromatography
Storage buffer PBS
Storage conditions For long term storage, the antibody should be stored at -20℃ and is stable for 12 months from
the date of receipt. Avoid repeated freeze-thaw cycles. For short term storage, keep at 4oC for a week should be fine.
Application Dilution 1:1, 000-1:100, 000 (platform dependent, customers must test the optimal concentration on their own platform)

Additional information

Size

100µg, 1mg

Background information

Influenza B viruses are separated into two distinct genetic lineages (Yamagata and Victoria) on the basis of differences in the HA glycoprotein.  Influenza B viruses from both lineages have co-circulated during most influenza seasons since the 1980s.Influenza viruses undergo constant genetic change, which has substantial impact on induced immunity and considerations for vaccine composition.  Two main types of changes are recognized.  Point mutations and recombination events occur in the viral genome, resulting in constant emergence of new virus variants.  This phenomenon is termed “antigenic drift”.   While it occurs among both influenza A and B viruses, influenza A viruses undergo antigenic drift more rapidly than influenza B viruses.  Frequent emergence of antigenic variants through antigenic drift is the virologic basis for seasonal influenza epidemics, and necessitates consideration of adjustment of vaccine viruses each season.

Datasheet

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Validation data

Validation data Download

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