Protein Name: Recombinant SARS-CoV-2 Nucleocapsid Protein, Lambda variant (P13L, R203K, G204R, G214C)
Protein Purification: Full-length SARS-CoV-2 Nucleocapsid protein, Met1-Ala419, with point mutations P13L, R203K, G204R, G214C and a C-terminal His-tag. P13L, R203K, G204R, G214C mutations are the same NP mutations which were identified on the SARS-CoV-2 Lambda variant (C.37) which emerged in Peru in August 2020.
Alternative Name: Protein N, NC, Lambda variant
Protein Construction: N protein with C-terminal His-tag
Endotoxin: <0.1 EU/ug
Expression Host: E. coli
Protein type: Recombinant
Purification tag: His-tag
Regulation restrictions: For research use only
Shipping: Recombinant proteins are provided as frozen liquid and will be shipped out with dry ice
Stability and storage: The protein is stable in a liquid state at -70℃ for 12 months. Avoid repeated freeze-thaw cycles
The nucleocapsid (N) protein is the structural component of the viral structure and it primarily functions to bind coronavirus RNA genome. The N protein is the most abundant protein in coronavirus. It is normally very conserved and is highly immunogenic phosphoprotein. It is also involved in CoV replication cycle and the host cellular response to viral infection. The localization of N to the endoplasmic reticulum (ER)-Golgi region has proposed a function for it in assembly and budding. This protein can be used as a marker for diagnostic tests for Covid-19.