Exonbio has developed SARS-CoV-2 Nucleocapsid recombinant monoclonal antibodies for the global IVD and research communities in support of efforts to combat the pandemic. The SARS–CoV–2 nucleocapsid (N) protein is highly homologous to the N protein of SARS–CoV, which is essential for viral RNA replication and packaging into new virions. By using Exonbio’s SPIN® technology platform, highly specific antibodies from plasma cells are generated against nucleocapsid protein of SARS-CoV-2. The recombinant nucleocapsid antibodies developed has no cross reactivity to human coronavirus nucleocapsid protein.
SARS-CoV-2 N-protein IgG mAbs
Clone ID | Isotype | Species | EC50 (ng/ml) |
NP11A2 | IgG,K | Rabbit | 0.57 |
NP11B6 | IgG,K | Rabbit | 0.60 |
NP11H9 | IgG,K | Rabbit | 0.84 |
NP4D2 | IgG,K | Rabbit | 0.95 |
NP11D9 | IgG,K | Rabbit | 0.96 |
NP11E9 | IgG,K | Rabbit | 0.97 |
NP4D8 | IgG,K | Rabbit | 1.02 |
NP11E4 | IgG,K | Rabbit | 1.17 |
NP4A6 | IgG,K | Rabbit | 1.37 |
NP4G8 | IgG,K | Rabbit | 1.55 |
NP7B1 | IgG,K | Rabbit | 2.33 |
NP4G6 | IgG,K | Rabbit | 2.35 |
NP7E2 | IgG,K | Rabbit | 2.87 |
NP4H8 | IgG,K | Rabbit | 3.11 |
NP4B9 | IgG,K | Rabbit | 3.52 |
NP7C3 | IgG,K | Rabbit | 3.56 |
Please reach out to us at antibody@exonbio.com for more information about our SARS-CoV-2 Nucleocapsid protein monoclonal antibodies.
Epitope Mapping
High-affinity monoclonal antibodies that fall in different epitope bins allow for antibody pairing for the development of ELISA kit. For detailed Nucleocapsid mAb pairing & clone information contact us.

Validation Data
ELISA: Nucleocapsid protein IgG mAbs are high affinity, with EC50 range between 0.5-3.5 ng/ml.

Biacore 3000: Crude supernatants containing rabbit monoclonal anti-NP antibodies were captured on protein A chip and nucleocapsid protein was injected at concentration of 300nM.
