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Research Teams at Janssen Harness Exonbio’s SPIN® Technology for Monoclonal Antibodies Against Human Spermine Oxidase

Research Teams at Janssen Harness Exonbio’s SPIN® Technology for Monoclonal Antibodies Against Human Spermine Oxidase

by Raju | Nov 14, 2025 | rabbit antibody

Spermine oxidase (SMOX) is an enzyme that converts the polyamine spermine to spermidine, producing reactive hydrogen peroxide and aldehydes as byproducts that can damage DNA and other biomolecules. SMOX activity is linked to DNA damage, inflammation, and...
Research Teams at Janssen Harness Exonbio’s SPIN® Technology for Monoclonal Antibodies Against Human Spermine Oxidase

Beyond Traditional Approaches: Promising Monoclonal Antibodies for Alzheimer’s Care

by Krisha Doshi | Jul 7, 2023 | rabbit antibody

Alzheimer’s disease is a neurodegenerative disease characterized by abnormal protein deposit aggregates in the brain tissue of patients. In particular, amyloid β-protein (Aβ) has been associated with the pathogenesis of Alzheimer’s. These Aβ molecules can aggregate...
The Distinctive Immune Systems Of Rabbits And Chickens Made Them Good Choices For Antibody Development

The Distinctive Immune Systems Of Rabbits And Chickens Made Them Good Choices For Antibody Development

by | Aug 6, 2017 | chicken monoclonal antibody, rabbit antibody

All jawed vertebrates use immunoglobulins (Ig) produced by B-lymphocytes for acquired immunity. Immunoglobulins are glycoproteins, consisting of two heavy and two light chains, bonded together by disulfide bonds, and often drawn in a cartoon as a “Y”. Immunity...
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