Anti-SARS-CoV-2 Nucleocapsid Antibody, Rabbit monoclonal, 11A7

CV-11A7NPCV-11A7NP

$350.00$1,500.00

Product Name Anti-SARS CoV-2 Nucleocapsid Antibody, Rabbit Monoclonal, 11A7
Catalog Number CV-11A7NPCV-11A7NP
Immunogen Nucleocapsid Protein (2019-nCoV Nucleocapsid Protein, Catalog # 19CoV-N150)
Host Rabbit
Preparation Recombinant monoclonal antibody expressed in HEK293F cells and purified by protein A affinity chromatography.
Applications Any application that detects COVID-19 virus, pseudo virus, and COVID19 native nucleocapsid protein. Does not detect denatured nucleocapsid protein.
Reactivity SARS CoV-2 nucleocapsid protein
Isotype rabbit IgG, kappa
Conjugation Unconjugated
Clonality Monoclonal
Concentration 1mg/ml
Purification Protein A affinity chromatography
Storage buffer PBS
Storage conditions For long term storage, the antibody should be stored at -20℃ and is stable for 12 months from the date of receipt. Avoid repeated freeze-thaw cycles. For short term storage, keep at 4oC for a week should be fine.
Application Dilution 1:1,000-1:100,000 (platform dependent, customers have to test the optimal concentration on their own platform)

Additional information

Size

100µg, 1mg

Background information

The nucleocapsid (N) protein is the structural component of the viral structure and it primarily functions to bind coronavirus RNA genome. The N protein is the most abundant protein in coronavirus. It is normally very conserved and is highly immunogenic phosphoprotein. It is also involved in CoV replication cycle and the host cellular response to viral infection. The localisation of N to the endoplasmic reticulum (ER)-Golgi region has proposed a function for it in assembly and budding. This protein can be used as a marker for diagnostic tests for Covid-19.

References:

  1. https://virologyj.biomedcentral.com/articles/10.1186/s12985-019-1182-0

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