Human ACE2 Protein



Protein Name Recombinant Human ACE2 Protein
Catalog Number 19CoV-A10019CoV-A100
Alternative Name Angiotensin-converting enzyme 2, hACE2
Purity 95% or above
Protein Construction Human ACE2 protein containing Gln18-Asp615 (Accession # Q9BYF1-1) C-terminal fusion with rabbit IgG Fc
Endotoxin <0.1 EU per ug of protein as determined by LAL method
Origin Species Homo sapiens (Human)
Expression Host HEK293F
Protein type Recombinant
Purification tag C-terminal rabbit IgG Fc. Protein A column purified
Molecule Mass Predicted molecular weight 194 kD
Regulation restrictions For research use only
Shipping Recombinant proteins are provided as frozen liquid and will be shipped out with dry ice.
Stability and storage The protein is stable in a liquid state at -70℃ for 12 months. Avoid repeated freeze-thaw cycles.



Additional information


100µg, 1mg

Background information

The protein encoded by this gene belongs to the angiotensin-converting enzyme family of dipeptidyl carboxydipeptidases and has considerable homology to human angiotensin 1 converting enzyme. This secreted protein catalyzes the cleavage of angiotensin I into angiotensin 1-9, and angiotensin II into the vasodilator angiotensin 1-7. ACE2 is known to be expressed in various human organs, and its organ- and cell-specific expression suggests that it may play a role in the regulation of cardiovascular and renal function, as well as fertility. In addition, the encoded protein is a functional receptor for the spike glycoprotein of the human coronavirus HCoV-NL63 and the human severe acute respiratory syndrome coronaviruses, SARS-CoV and SARS-CoV-2, the latter is the causative agent of coronavirus disease-2019 (COVID-19). Multiple splice variants have been found for this gene and the dACE2 (or MIRb-ACE2) splice variant has been found to be interferon inducible.


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