Influenza A NP Monoclonal Antibody (3G8H1)
$350.00 – $750.00
| Protein Name | Influenza A NP Monoclonal Antibody (3G8H1) |
| Catalog Number | FA-3G8H1NPFA-3G8H1NP |
| Immunogen | Influenza A Nucleoprotein |
| Host | Rabbit |
| Preparation | Recombinant monoclonal antibody expressed in HEK293F cells and purified by protein A affinity chromatography |
| Applications | Any application that detects Influenza A virus, pseudo virus, and Influenza A native nucleocapsid protein. Does not detect denatured nucleocapsid protein. |
| Reactivity | Influenza A nucleocapsid protein |
| Isotype | rabbit IgG, kappa |
| Conjugation | Unconjugated |
| Clonality | Monoclonal |
| Concentration | 1mg/ml |
| Purification | Protein A affinity chromatography |
| Storage buffer | PBS |
| Storage conditions | For long term storage, the antibody should be stored at -20℃ and is stable for 12 months from the date of receipt. Avoid repeated freeze-thaw cycles. For short term storage, keep at 4oC for a week should be fine. |
| Application Dilution | 1:1,000-1:100,000 (platform dependent, customers must test the optimal concentration on their own platform) |
Additional information
| Size | 100µg, 1mg |
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Background information
The nucleoprotein (NP) of Influenza virus encapsulates the negative strand of the viral RNA and is essential for replicative transcription. It may also be involved in other essential functions throughout the virus life cycle. As well as binding ssRNA, NP is able to self associate to form large oligomeric complexes. NP is able to interact with a variety of other macromolecules of both viral and cellular origins. It binds the PB1 and PB2 subunits of the polymerase and the matrix protein M1. “NP has also been shown to interact with at least four cellular polypeptide families: nuclear import receptors of the importin class, filamentous (F) actin, the nuclear export receptor CRM1 and a DEAD box helicase BAT1/UAP56” (Portela et al 2002).
Datasheet
| Datasheet | Download |
Validation data
| Validation data | Download |